Objective: To report a case of Mucosa-Associated Lymphoid Tissue (MALT) lymphoma of the nasopharynx in a young woman, and its clinical presentation, laboratory findings and management.

Design: Case Report

Setting: Tertiary Government Training Hospital

Patient: One

Result: A 21-year-old woman with a four-month history of right lateral neck mass managed as a case of clinically diagnosed pulmonary tuberculosis consulted us. Nasal endoscopy showed an erythematous, non-ulcerating exophytic mass in the nasopharynx. Histopathologic, immune histochemical and PET-CT imaging studies confirmed MALT. She completed seven sessions of chemotherapy and is currently in complete remission.

Conclusion: MALT lymphoma of the nasopharynx is rare and may mimic other head and neck tumors both clinically and histologically. A high index of suspicion, thorough examination of Waldeyer’s ring, and confirmatory immunohistochemistry are essential for timely and accurate diagnosis of this uncommon but treatable malignancy.

Ma Katrina C Tagata completed her medical degree from Saint Louis University and her residency training in Otolaryngology- Head and Neck Surgery in Victoriano Luna Medical Center. She passed her diplomate board exam in 2024 and was ranked 7 nationwide. She currently serves as a junior consultant in Victoriano Luna Medical Center, Philippines.